References for Astragalus Membranaceus- Astro product - Hekma Center

References for Astragalus Membranaceus- Astro product

References for Astragalus Membranaceus- Astro product

– Ahmed MS, et al. Treatment of idiopathic membranous nephropathy with the herb Astragalus membranaceus. Am J Kidney Dis. (2007).

– Astragalus membranaceus, Monograph, Alternative Medicine Review 2003, Vol. 8, 1: 72-77.

– Auyeung KK, Law PC, Ko JK. Astragalus saponins induce apoptosis via an ERKindependent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line. Int J Mol Med. [Online] 2009 Feb;23(2):189-96.

– Auyeung KK, Mok NL, Wong CM, Cho CH, Ko JK. Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells. Int J Mol Med. 2010 Sep;26(3):341-9.

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– Changtai Zhu, Hao Cao, Xifa Zhou, Chunlei Dong, Judong Luo, Changsong Zhang, Jinming Liu, and Yang Ling. Meta-Analysis of the Clinical Value of Danshen Injection and Huangqi Injection in Liver Cirrhosis. Evidence-Based Complementary and Alternative Medicine Volume 2013.

– Chan JY, Lam FC, Leung PC, Che CT, Fung KP. Antihyperglycemic and antioxidative effects of a herbal formulation of Radix Astragali, Radix Codonopsis and Cortex Lycii in a mouse model of type 2 diabetes mellitus. Phytother.Res 2009;23(5):658-665.

– Chao M, Zou D, Zhang Y, Chen Y, Wang M, Wu H, Ning G, Wang W. Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients. Endocrine. 2009;36(2):268-274.

– Chen CC, Lee HC, Chang JH, Chen SS, Li TC, Tsai CH, Cho DY, Hsieh CL. Chinese Herb Astragalus membranaceus Enhances Recovery of Hemorrhagic Stroke: Double-Blind, Placebo-Controlled, Randomized Study. Evid Based Complement Alternat Med. 2012;2012:708452.

– Cheng XD, Hou CH, Zhang XJ, Xie HY, Zhou WY, Yang L, Zhang SB, Qian RL. Effects of Huangqi (Hex) on inducing cell differentiation and cell death in K562 and HEL cells. Acta Biochim Biophys Sin (Shanghai). 2004 Mar;36(3):211-7.

– Chen H, Weng L. Comparison on efficacy in treating liver fibrosis of chronic hepatitis B between Astragalus Polygonum anti-fibrosis decoction and jinshuibao capsule. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Apr;20(4):255-7.

– Chen HW, Lin IH, Chen YJ, Chang KH, Wu MH, Su WH, Huang GC, Lai YL. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II doubleblind, randomized placebo-controlled study. Clin Invest Med. 2012 Feb 1;35(1):E1-11.

– Chen LP, Zhou QL, Yang JH. Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome. Zhong Nan Da Xue Xue Bao Yi Xue Ban. (2004).

– Chen LX, Liao JZ, Guo WQ. Effects of Astragalus membranaceus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action. Zhongguo Zhong. Xi. Yi Jie He Za Zhi. 1995; 15(3): 141-143.

– Chen XJ, Bian ZP, Lu S, Xu JD, Gu CR, Yang D, Zhang JN. Cardiac protective effect of Astragalus on viral myocarditis mice: comparison with Perindopril.  2006.

– Chen XJ, Meng D, Feng L, Bian YY, Li P. Protective effect of astragalosides on myocardial injury by isoproterenol in SD rats. Am J Chin Med. 2006;34(6):1015-25.

– Chen L, Xie C, Wu L. Point injection of injectio radici astragali for treatment of postchemotherapy adverse reactions. J Tradit Chin Med. 2005 Mar;25(1):21-2.

– Cho JH, Cho CK, Shin JW, Son JY, Kang W, Son CG. Myelophil, an extract mix of Astragali Radix and Salviae Radix, ameliorates chronic fatigue: a randomised, doubleblind, controlled pilot study. Complement Ther Med. 2009 Jun;17(3):141-6. .

– Cho WC, Leung KN. In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett. 2007 Jul 8;252(1):43-54.

– Chen W, Li Y, Yu M. Astragalus polysaccharides: an effective treatment for diabetes prevention in NOD mice. 2008.

– Chu D, Sun Y, Lin J et al. F3, a fractionated extract of Astragalus membranaceus,potentiates lymphokine-activated killer cell cytotoxicity generated by low-dose recombinant interleukin-2. Zhong Xi Yi Jie He Za Zhi 1990;10:34-36, 35.

– Chu DT, Lepe-Zuniga J, Wong WL et al. Fractionated extract of Astragalus membranaceus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2. J Clin Lab Immunol 1988;26:183-187.

– Chu DT, Lin JR, Wong W. The in vitro potentiation of LAK cell cytotoxicity in cancer and aids patients induced by F3, a fractionated extract of Astragalus membranaceus. Zhonghua Zhong Liu Za Zhi 1994;16:167-171.

– Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J. Clin. Lab. Immunol., 1988,25(3):125-129.

– Cui, X, Wang, Y, Kokudo, N, Fang, D, Tang, W. Traditional Chinese medicine and related active compounds against hepatitis B virus infection. Biosci.Trends 2010;4(2):39-47.

– Dang SS, Jia XL, Song P, Cheng YA, Zhang X, Sun MZ, Liu EQ. Inhibitory effect of emodin and Astragalus polysaccharide on the replication of HBV. World J Gastroenterol. 12-7-2009;15(45):5669-5673.

– Dang SS, Zhang X, Jia XL, Cheng YA, Song P, Liu EQ, He Q, Li ZF. Protective effects of emodin and astragalus polysaccharides on chronic hepatic injury in rats. Chin Med J 2008 Jun 5;121(11):1010-4.

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– Deng Y, Chen HF. Effects of Astragalus injection and its ingredients on proliferation and Akt phosphorylation of breast cancer cell lines. Zhong Xi Yi Jie He Xue Bao. 2009 Dec;7(12):1174-80.

– Duan P, Wang Z-m. Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor. Zhongguo Zhong Xi Yi Jie He Za Zhi 2002, 22:515-517.

– Effects of Huangqi injection on infection factors in children with acute lymphoblastic leukemia. Zhang XJ, Yan M, Liu Y, Wang XM, Nuriding H. Zhongguo Dang Dai Er Ke Za Zhi. 2014 Feb;16(2):147-51.

– Fengqin L, Yulin W, Xiaoxin Z, Youpeng J, Yan C, Qing-qing W, Hong C, Jia S, Lei H. The heart-protective mechanism of Qishaowuwei formula on murine viral myocarditis induced by CVB3. J Ethnopharmacol. 2-3-2010;127(2):221-228.

– Fujiwara Y, et al. Triterpenoids isolated from Zizyphus jujuba inhibit foam cell formation in macrophages . J Agric Food Chem. (2011) .

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– Gao, S. R., Bu, J. H., and Zhu, L. Z. Preliminary exploration on effect of qilian decoction in intervention treatment of diabetes mellitus type 2 with insulin resistance and its influence on related inflammatory cytokines. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Jul;24(7):593-5.

– Guan Y, Zhou Z, Zhang C, Ruan Y, Wu Z. Effect of A-L tonic capsule on DNA content in rat experimental hepatocarcinogenesis. J Huazhong.Univ Sci Technolog.Med Sci 2002;22(1):12-3, 16.

– Guo L, Bai SP, Zhao L, Wang XH. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival. Med Oncol. 2012 Sep;29(3):1656-62.

– Han, L. and Chen, K. J. The protective effects of yi-xin-kang capsule on the structure and function of rat myocardial mitochondria. Zhongguo Zhong.Yao Za Zhi. 2001;26(11):773-777.

– He Y, Du M, Gao Y, Liu H, Wang H, Wu X, Wang Z. Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. PLoS One. 2013 Oct 4;8(10):e76495.

– Hikino H, Funayama S, and Endo K. Hypotensive principle of Astragalus and Hedysarum roots. Planta Medica 1976;30:297-302.

– Hong YH. Oriental Materia Medica: A Concise Guide, Long Beach, CA, Oriental Healing Arts Institute, 1986.

– Hoo RL., Wong JY, Qiao C, Xu A, Xu H, Lam KS.The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity. Nutr Metab (Lond) 2010;7:67.

– Hou YD, Ma GL, Wu SH et al. Effect of Radix Astragali seu Hedysari on the interferon system. Chin Med J (Engl) 1981;94:35-40.

– Huang CL, Lu YP. Effect of Astragalus injection on insulin resistance in auxiliary treating patients with diabetes mellitus type 2. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2003;23(10):779-780.

– Huang GC, et al. Effects of Dang-Gui-Bu-Xue-Tang, an herbal decoction, on iron uptake in iron-deficient anemia. Drug Des Devel Ther. 2016 Mar 2;10:949-57.

– Huang WH, Liao WR, Sun RX. Astragalus polysaccharide induces the apoptosis of human hepatocellular carcinoma cells by decreasing the expression of Notch1. Int J Mol Med. Aug 2016;38(2):551-557.

– Jiang RH, Xu HB, Fu J. Outcomes of Chinese herb medicine for the treatment of multidrug-resistant tuberculosis: a systematic review and meta-analysis. Complement Ther Med. 2015 Aug;23(4):544-54.

– Jia, W., Gao, W. Y., and Xiao, P. G. Antidiabetic drugs of plant origin used in China: compositions, pharmacology, and hypoglycemic mechanisms. Zhongguo Zhong.Yao Za Zhi. 2003;28(2):108-113.

– Kim JH, Kim MH, Yang G, Huh Y, Kim SH, Yang WM. Effects of topical application of Astragalus membranaceus on allergic dermatitis. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):151-6.

– Ko JK, Chik CW. The protective action of radix Astragalus membranaceus against hapten-induced colitis through modulation of cytokines. Cytokine. 2009 Aug;47(2):85-90.

– Ko JK, Lam FY, Cheung AP. Amelioration of experimental colitis by Astragalus membranaceus through anti-oxidation and inhibition of adhesion molecule synthesis. World J Gastroenterol. [Online] 2005 Oct 7;11(37):5787-94.

– Kusum, M., Klinbuayaem, V., Bunjob, M., and Sangkitporn, S. Preliminary efficacy and safety of oral suspension SH, combination of five chinese medicinal herbs, in people living with HIV/AIDS ; the phase I/II study. J.Med.Assoc.Thai. 2004;87(9):1065-1070.

– Lau BH, Ruckle HC, Botolazzo T, Lui PD. Chinese medicinal herbs inhibit growth of murine renal cell carcinoma. Cancer Biother 1994;9:153-61.

– Law PC, Auyeung KK, Chan LY, et al. Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells. BMC Complement Altern Med. 2012;12:160.

– Leehey DJ, Casini T, Massey D. Remission of membranous nephropathy after therapy with Astragalus membranaceus. Am J Kidney Dis. 2010 Apr;55(4):772.

– Lee KY, Jeon YJ. Macrophage activation by polysaccharide isolated from Astragalus membranaceus. Int Immunopharmacol 2005;5:1225-1233.

– Lee SJ, Oh SG, Seo SW, Ahn HJ, Geum D, Cho JJ, Park CS. Oral administration of Astragalus membranaceus inhibits the development of DNFB-induced dermatitis in NC/Nga mice. 2007 Aug;30(8):1468-71.

– Lei Y, Gao Q, Li YS. Study on effects of Astragalus, Angelica and their combination on vascular endothelial cell proliferation in vitro. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 Oct;23(10):753-6.

– Lei ZY, Qin H, Liao JZ. Action of Astragalus membranaceus on left ventricular function of angina pectoris. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Apr;14(4):199-202, 195.

– Leung A. Foster S. Encyclopedia of Common Natural Ingredients, John Wiley & Sons, 1996, Inc. p. 50-53.

– Liang HY, Hou F, Ding YL, Zhang WN, Huang XH, Zhang BY, Liu Y. Clinical evaluation of the antioxidant activity of astragalus in women with gestational diabetes. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jul;29(7):1402-4.

– Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors’ expression. J Huazhong.Univ Sci Technolog.Med Sci 2004;24(4):379-384.

– Li HQ, Qiu JD, Yang LH. Regulation of Astragalus heteropolysaccharides on synoviocytes apoptosis and proinflammatory cytokine secretion of rats with adjuvant arthritis. Yao Xue Xue Bao. [Online] 2009 Jul;44(7):731-6.

– Li M, Ma JJ, Zhao XL, Zhu Y. Treating lupus nephritis by a drug pair of radix astragali and rehmanniae radix combined with glucocorticoid: a preliminary clinical study. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Aug;34(8):956-9. .

– Li M, Wang W, Xue J, Gu Y, Lin S. Meta-analysis of the clinical value of Astragalus membranaceus in diabetic nephropathy. J Ethnopharmacol. 2011 .

– Lin LZ. He XG. Lindenmair M. et al. Liquid chromatography-electrospray ionization mass spectrometry study of flavonoids of the roots of Astragalus mongholicus and A, membranaceus. J. Chromatogr. A 2000, 876: 87-95.

– Li SM, Yan JX, Yang L. Effects of Astragalus injection on renal tubular function in patients with IgA nephropathy. Zhongguo Zhong Xi Yi Jie He Za Zhi (2006).

– Li S, Yin XX, Su T, Cao C, Li X, Rao XR, Li X. Therapeutic effect of Astragalus and Angelica mixture on the renal function and TCM syndrome factors in treating stage 3 and 4 chronic kidney disease patients. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Jul;3.

– Lin Y, Ning XF, Yu W, Li ZP. Effects of astragaloside IV on cardiac collagen content in rats with acute myocardial infarction and its mechanisms. Chin Pharm J (Chin) 2008;43:833-837.

– Lin Y, Wang B, Luo XQ. Clinical study of astragalus’s preventing the recurrence of asthma in children. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Aug;31(8):1090-2.

– Lien AS, Jiang YD, Chih-Hsin Mou MS, Sun MF, Bih-Shya Gau RN, Yen HR. Integrative Traditional Chinese Medicine Therapy Reduces the Risk of Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus. J Ethnopharmacol. 2016 Jun 20. pii: S0378- 8741(16)3.

– Li, HB, Ge YK, Zhang L, Zheng XX. Astragaloside IV improved barrier dysfunction induced by acute high glucose in human umbilical vein endothelial cells. Life Sci 8-15-2006;79(12):1186-1193.

– Li MR, Yu YR, Deng G. Astragalus membranaceus improves endothelial-dependent vasodilator function in obese rats. Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jan;30(1):7- 10.

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– Li SQ, He H. Effects of Astragalus Membranacus on superoxide dismutase and lipid peroxide in patients with pectoris. Chin J Integr Med Cardio-Cerebrovasc Dis (Chin) 2003; 1231-1234.

– Li SQ, Yuan RX, Gao H. Clinical observation on the treatment of ischemic heart disease with Astragalus membranaceus. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Feb;15(2):77-80.

– Liu H, Wei W, Sun WY, Li X. Protective effects of astragaloside IV on porcine-seruminduced hepatic fibrosis in rats and in vitro effects on hepatic stellate cells. J Ethnopharmacol. 4-21-2009;122(3):502-508.

– Liu M, Wu K, Mao X, Wu Y, Ouyang J. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle. J Ethnopharmacol. 2010 Jan 8;127(1):32-7.

– Liu WJ, Liu B, Guo QL., Zhang YC, Yuan YJ, Fu XD, Deng ZH, Lin J. Influence of ganciclovir and astragalus membranaceus on proliferation of hematopoietic progenitor cells of cord blood after cytomegalovirus infection in vitro. Zhonghua Er.Ke.Za Zhi. 2004;42(7):490-494.

– Liu, Y. H., Yang, L., and Liu, J. [Clinical observation on treatment of early diabetic nephropathy by milkvetch injection combined with captopril]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2005;25(11):993-995.

– Liu ZL, Liu ZJ, Liu JP, Kwong JS. Herbal medicines for viral myocarditis. Cochrane Database Syst.Rev. 2012;11:CD003711.

– Li WZ, et al. Protective effect of extract of Astragalus on learning and memory impairments and neurons’ apoptosis induced by glucocorticoids in 12-month-old male mice. Anat Rec (Hoboken). 2011 .

– Lu, D. C., Su, Z. J., and Rui, T. Effect of jian yan ling on serum lipids, apoprotein and lipoprotein-a. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(3):142-144, 131-2.

– Luo Z, et al. Astragalus membranaceus prevents daunorubicin-induced apoptosis of cultured neonatal cardiomyocytes: role of free radical effect of Astragalus membranaceus on daunorubicin cardiotoxicity. Phytother Res. (2009) .

– Lu ZM, Qian XH, Chen ZW, Zhang CH, Guo LS, Chen J. Prospective clinical study of radix astragali and its compound prescription for treatment of β-thalassemia in children. Zhongguo Dang Dai Er Ke Za Zhi. 2012 May;14(5):344-9.

– Lu ZM, Yu YR, Tang H, Zhang XX. The protective effects of Radix Astragali and Rhizoma Ligustici chuanxiong on endothelial dysfunction in type 2 diabetic patients with microalbuminuria. Sichuan Da Xue Xue Bao Yi Xue Ban. 2005 Jul;36(4):529-32.

– Mao SP, Cheng KL, Zhou YF. Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3.

– Mao XQ, Yu F, Wang N, Wu Y, Zou F, Wu K, Liu M, Ouyang JP. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism. Phytomedicine. 2009 May;16(5):416-25.

– Matkovic Z, Zivkovic V, Korica M, Plavec D, Pecanic S, Tudoric N. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res. 2010 Feb;24(2):175-81.

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– Motomura K, Fujiwara Y, Kiyota N, Tsurushima K, Takeya M, Nohara T, Nagai R, Ikeda T. Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products. J Agric Food Chem. 2009 Sep 9;57(17):7666-72. .

– Nan Fang Yi Ke Da Xue Xue Bao. Integrated treatment of traditional Chinese medicine and western medicine for early- and intermediate-stage diabetic nephropathy. Zhao L, et al . 2007 .

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– Ono K, Nakane H, Meng ZM, Ose Y, Sakai Y, Mizuno M. Differential inhibitory effects of various herb extracts on the activities of reverse transcriptase and various deoxyribonucleic acid (DNA) polymerases. Chem Pharm Bull (Tokyo). 1989 Jul;37(7):1810-2.

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– Pan HF, Fang XH, Li WX, Ye DQ, Wu GC, Li XP.Radix Astragali: a promising new treatment option for systemic lupus erythematosus. Med Hypotheses. 2008 Aug;71(2):311-2.

– Pao LH, Hu OY, Fan HY, Lin cc, Liu LC, Huang PW. Herb-drug interaction of 50 chinese herbal medicines on CYP3A4 activity in vitro and in vivo. AM J Chin Med. 2012; 40(1). 57-75.

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– Qian ZW, Mao SJ, Cai XC, Zhang XL, Gao FX, Lu MF, Shao XS, Li YY, Yang XK, Zhuo YA, et al. Viral etiology of chronic cervicitis and its therapeutic response to a recombinant interferon. Chin Med J (Engl). 1990 Aug;103(8):647-51.

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– Qiu LH, Xie XJ, Zhang BQ. Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation. Biol Pharm Bull. 2010 .

– Qu Wen, Song Wenxiu. Effects of Huangqi injection with Tapazole on treatment of Graves′ disease complication Leukopenia. Tianjin Pharmacy 2000-04.

– Qu ZL, Dong H, Wang SD. Effects of astragalus injection on renal function in patients after cardiac valve replacement with cardiopulmonary bypass. Zhongguo Zhong Xi Yi Jie He Za Zhi. (2009) .

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– Shen, P., Liu, M. H., Ng, T. Y., Chan, Y. H., and Yong, E. L. Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro. J Nutr 2006;136(4):899-905.

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– Su L, Mao JC, Gu JH. Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis. Zhong Xi Yi Jie He Xue Bao. 2007 .

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